Treating the Underlying Causes of Age-Related Disease
Cyclarity develops easy-to-use drugs that prevent common age-related conditions such as atherosclerosis, heart-attack and stroke by addressing the root cause - a build-up of arterial plaque.
The company's technology removes arterial plaque by clearing the non-degradable cholesterol that accumulates within cells in the arterial walls.
Cyclarity's long-term goal is to deliver a simple and affordable preventive therapy for the world.

Our products are based on novel derivatives of a well-known, safe compound, and a new way of looking at cardiovascular disease.
Curing age-related disease
- through damage repair
- using simple, direct, rationally designed drugs
... starting with
- the first true disease-modifying treatment for atherosclerosis
... based on
- a novel class of well-known, safe compounds called cyclodextrins
... driven by
- a new perspective on cardiovascular disease
- with a launch of $4M
- to carry development through candidate selection and lead testing
- Raise of additional $10M
- to carry development through to initial filings with regulatory agency for human clinical trials
- Underdog Pharmaceuticals rebrands to Cyclarity Therapeutics
Cyclarity is continuing to develop technology to treat, cure, and reverse atherosclerosis.